D Spigel

Affiliations

Tennessee Oncology, Chattanooga and Sarah Cannon Research Institute, Nashville, USA.

Publications (11)

Randomized Phase 2 Studies of Checkpoint Inhibitors Alone or in Combination With Pegilodecakin in Patients With Metastatic NSCLC (CYPRESS 1 and CYPRESS 2).

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer

Avec: David Spigel , Robert Jotte , John Nemunaitis , Merrill Shum , Jeffrey Schneider , Jerome Goldschmidt , Jennifer Eisenstein , David Berz , Lasika Seneviratne , Matei Socoteanu , Viralkumar Bhanderi , Kartik Konduri , Meng Xia , Hong Wang , Rebecca R Hozak , Ivelina Gueorguieva , David Ferry , Leena Gandhi , Bo H Chao , Igor Rybkin

Efficacy and safety of first-line avelumab in patients with advanced non-small cell lung cancer: results from a phase Ib cohort of the JAVELIN Solid Tumor study.

Journal for immunotherapy of cancer

Avec: Claire F Verschraegen , Guy Jerusalem , Edward F McClay , Nicholas Iannotti , Charles H Redfern , Jaafar Bennouna , Franklin L Chen , Karen Kelly , Janice Mehnert , John C Morris , Matthew Taylor , David Spigel , Ding Wang , Hans Juergen Grote , Dongli Zhou , Neru Munshi , Marcis Bajars , James L Gulley

Durable responders in advanced NSCLC with elevated TMB and treated with 1L immune checkpoint inhibitor: a real-world outcomes analysis.

Journal for immunotherapy of cancer

Avec: Richard S P Huang , David P Carbone , Gerald Li , Alexa Schrock , Ryon P Graf , Liangliang Zhang , Karthikeyan Murugesan , Jeffrey S Ross , Khaled Tolba , Jacob Sands , Geoffrey R Oxnard , David Spigel

A Phase Ib Study Assessing the Safety, Tolerability, and Efficacy of the First-in-Class Wee1 Inhibitor Adavosertib (AZD1775) as Monotherapy in Patients with Advanced Solid Tumors.

Targeted oncology

Avec: Todd M Bauer , Kathleen N Moore , Janet S Rader , Fiona Simpkins , Alain C Mita , J Thaddeus Beck , Lowell Hart , Quincy Chu , Amit Oza , Anna V Tinker , Esteban Rodrigo Imedio , Sanjeev Kumar , Ganesh Mugundu , Suzanne Jenkins , Juliann Chmielecki , Suzanne Jones , David Spigel , Siqing Fu

Impact of Workforce Challenges and Funds Flow on Cancer Clinical Trial Development and Conduct.

American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting

Avec: Nathan A Pennell , Connie Szczepanek , David Spigel , Suresh S Ramalingam

In situ tumour arrays reveal early environmental control of cancer immunity.

Nature

Avec: Guadalupe Ortiz-Muñoz , Markus Brown , Catherine B Carbone , Ximo Pechuan-Jorge , Vincent Rouilly , Henrik Lindberg , Alex T Ritter , Gautham Raghupathi , Qianbo Sun , Tess Nicotra , Shreya R Mantri , Angela Yang , Jonas Doerr , Deepti Nagarkar , Spyros Darmanis , Benjamin Haley , Sanjeev Mariathasan , Yulei Wang , Carlos Gomez-Roca , Carlos Eduardo de Andrea , David Spigel , Thomas Wu , Lelia Delamarre , Johannes Schöneberg , Zora Modrusan , Richard Price , Shannon J Turley , Ira Mellman , Christine Moussion

Outcomes with durvalumab by tumour PD-L1 expression in unresectable, stage III non-small-cell lung cancer in the PACIFIC trial.

Annals of oncology : official journal of the European Society for Medical Oncology

Avec: L Paz-Ares , A Spira , D Raben , D Planchard , B C Cho , M Özgüroğlu , D Daniel , A Villegas , D Vicente , R Hui , S Murakami , D Spigel , S Senan , C J Langer , B A Perez , A-M Boothman , H Broadhurst , C Wadsworth , P A Dennis , S J Antonia , C Faivre-Finn

Retrospective Assessment of a Serum Proteomic Test in a Phase III Study Comparing Erlotinib plus Placebo with Erlotinib plus Tivantinib (MARQUEE) in Previously Treated Patients with Advanced Non-Small Cell Lung Cancer.

The oncologist

Avec: Consuelo Buttigliero , Frances A Shepherd , Fabrice Barlesi , Brian Schwartz , Sergey Orlov , Adolfo G Favaretto , Armando Santoro , Vera Hirsh , Rodryg Ramlau , Adele R Blackler , Joanna Roder , David Spigel , Silvia Novello , Wallace Akerley , Giorgio V Scagliotti

Frontiers in oncology

Avec: Corey J Langer , Ajeet Gajra , Cesare Gridelli , Kartik Konduri , Daniel Morgensztern , David Spigel , Denis Talbot , Michael Thomas , Jared Weiss , Richard Pilot , Rafia Bhore , Marianne Wolfsteiner , Teng Jin Ong , Mark Socinski

Impact of subsequent immune checkpoint inhibitor treatment on overall survival with avelumab vs docetaxel in platinum-treated advanced NSCLC: Post hoc analyses from the phase 3 JAVELIN Lung 200 trial.

Lung cancer (Amsterdam, Netherlands)

Avec: Keunchil Park , Mustafa Özgüroğlu , Johan Vansteenkiste , David Spigel , James C-H Yang , Marcis Bajars , Mary Ruisi , Juliane Manitz , Fabrice Barlesi

Avelumab Versus Docetaxel in Patients With Platinum-Treated Advanced NSCLC: 2-Year Follow-Up From the JAVELIN Lung 200 Phase 3 Trial.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer

Avec: Keunchil Park , Mustafa Özgüroğlu , Johan Vansteenkiste , David Spigel , James C H Yang , Hidenobu Ishii , Marina Garassino , Filippo de Marinis , Aleksandra Szczesna , Andreas Polychronis , Ruchan Uslu , Maciej Krzakowski , Jong-Seok Lee , Luana Calabrò , Osvaldo Arén Frontera , Huiling Xiong , Marcis Bajars , Mary Ruisi , Fabrice Barlesi

Réseau de co-auteurs

David Spigel 10 collaborations

Marcis Bajars 3 collaborations

Fabrice Barlesi 3 collaborations

Kartik Konduri 2 collaborations

Keunchil Park 2 collaborations

Mustafa Özgüroğlu 2 collaborations

Johan Vansteenkiste 2 collaborations

Mary Ruisi 2 collaborations

Robert Jotte 1 collaboration

John Nemunaitis 1 collaboration

Merrill Shum 1 collaboration

Jeffrey Schneider 1 collaboration

Jerome Goldschmidt 1 collaboration

Jennifer Eisenstein 1 collaboration

David Berz 1 collaboration

Lasika Seneviratne 1 collaboration

Matei Socoteanu 1 collaboration

Viralkumar Bhanderi 1 collaboration

Meng Xia 1 collaboration

Hong Wang 1 collaboration

Rebecca R Hozak 1 collaboration

Ivelina Gueorguieva 1 collaboration

David Ferry 1 collaboration

Leena Gandhi 1 collaboration

Bo H Chao 1 collaboration

Igor Rybkin 1 collaboration

Claire F Verschraegen 1 collaboration

Guy Jerusalem 1 collaboration

Edward F McClay 1 collaboration

Nicholas Iannotti 1 collaboration

Charles H Redfern 1 collaboration

Jaafar Bennouna 1 collaboration

Franklin L Chen 1 collaboration

Karen Kelly 1 collaboration

Janice Mehnert 1 collaboration

John C Morris 1 collaboration

Matthew Taylor 1 collaboration

Ding Wang 1 collaboration

Hans Juergen Grote 1 collaboration

Dongli Zhou 1 collaboration

Neru Munshi 1 collaboration

James L Gulley 1 collaboration

Richard S P Huang 1 collaboration

David P Carbone 1 collaboration

Gerald Li 1 collaboration

Alexa Schrock 1 collaboration

Ryon P Graf 1 collaboration

Liangliang Zhang 1 collaboration

Karthikeyan Murugesan 1 collaboration

Jeffrey S Ross 1 collaboration

Khaled Tolba 1 collaboration

Jacob Sands 1 collaboration

Geoffrey R Oxnard 1 collaboration

Todd M Bauer 1 collaboration

Kathleen N Moore 1 collaboration

Janet S Rader 1 collaboration

Fiona Simpkins 1 collaboration

Alain C Mita 1 collaboration

J Thaddeus Beck 1 collaboration

Lowell Hart 1 collaboration

Quincy Chu 1 collaboration

Amit Oza 1 collaboration

Anna V Tinker 1 collaboration

Esteban Rodrigo Imedio 1 collaboration

Sanjeev Kumar 1 collaboration

Ganesh Mugundu 1 collaboration

Suzanne Jenkins 1 collaboration

Juliann Chmielecki 1 collaboration

Suzanne Jones 1 collaboration

Siqing Fu 1 collaboration

Nathan A Pennell 1 collaboration

Connie Szczepanek 1 collaboration

Suresh S Ramalingam 1 collaboration

Guadalupe Ortiz-Muñoz 1 collaboration

Markus Brown 1 collaboration

Catherine B Carbone 1 collaboration

Ximo Pechuan-Jorge 1 collaboration

Vincent Rouilly 1 collaboration

Henrik Lindberg 1 collaboration

Alex T Ritter 1 collaboration

Gautham Raghupathi 1 collaboration

Qianbo Sun 1 collaboration

Tess Nicotra 1 collaboration

Shreya R Mantri 1 collaboration

Angela Yang 1 collaboration

Jonas Doerr 1 collaboration

Deepti Nagarkar 1 collaboration

Spyros Darmanis 1 collaboration

Benjamin Haley 1 collaboration

Sanjeev Mariathasan 1 collaboration

Yulei Wang 1 collaboration

Carlos Gomez-Roca 1 collaboration

Carlos Eduardo de Andrea 1 collaboration

Thomas Wu 1 collaboration

Lelia Delamarre 1 collaboration

Johannes Schöneberg 1 collaboration

Zora Modrusan 1 collaboration

Richard Price 1 collaboration

Shannon J Turley 1 collaboration

Ira Mellman 1 collaboration

Christine Moussion 1 collaboration

L Paz-Ares 1 collaboration

A Spira 1 collaboration

D Raben 1 collaboration

D Planchard 1 collaboration

B C Cho 1 collaboration

M Özgüroğlu 1 collaboration

D Daniel 1 collaboration

A Villegas 1 collaboration

D Vicente 1 collaboration

R Hui 1 collaboration

S Murakami 1 collaboration

S Senan 1 collaboration

C J Langer 1 collaboration

B A Perez 1 collaboration

A-M Boothman 1 collaboration

H Broadhurst 1 collaboration

C Wadsworth 1 collaboration

P A Dennis 1 collaboration

S J Antonia 1 collaboration

C Faivre-Finn 1 collaboration

Consuelo Buttigliero 1 collaboration

Frances A Shepherd 1 collaboration

Brian Schwartz 1 collaboration

Sergey Orlov 1 collaboration

Adolfo G Favaretto 1 collaboration

Armando Santoro 1 collaboration

Vera Hirsh 1 collaboration

Rodryg Ramlau 1 collaboration

Adele R Blackler 1 collaboration

Joanna Roder 1 collaboration

Silvia Novello 1 collaboration

Wallace Akerley 1 collaboration

Giorgio V Scagliotti 1 collaboration

Corey J Langer 1 collaboration

Ajeet Gajra 1 collaboration

Cesare Gridelli 1 collaboration

Daniel Morgensztern 1 collaboration

Denis Talbot 1 collaboration

Michael Thomas 1 collaboration

Jared Weiss 1 collaboration

Richard Pilot 1 collaboration

Rafia Bhore 1 collaboration

Marianne Wolfsteiner 1 collaboration

Teng Jin Ong 1 collaboration

Mark Socinski 1 collaboration

James C-H Yang 1 collaboration

Juliane Manitz 1 collaboration

James C H Yang 1 collaboration

Hidenobu Ishii 1 collaboration

Marina Garassino 1 collaboration

Filippo de Marinis 1 collaboration

Aleksandra Szczesna 1 collaboration

Andreas Polychronis 1 collaboration

Ruchan Uslu 1 collaboration

Maciej Krzakowski 1 collaboration

Jong-Seok Lee 1 collaboration

Luana Calabrò 1 collaboration

Osvaldo Arén Frontera 1 collaboration

Huiling Xiong 1 collaboration